Collaborations with the Industry

Since 2000 our unit has actively participated in a number of multicenter clinical trials supported by funding agencies, the administration of which was carried out mostly through the Research Committee of the University of Thessalia. The projects are presented in the following table:

Year

Company

Title

2001

ZIMMER - ARTHROSIS

Integration of acetabular prosthesis on tantalium uncemented Hip Arthroplasty.

2001

NOVARTIS

An international, multicenter, stratifier, randomized, double-blind, double-dummy, parallel-group, 52-week gastrointestinal clinical safety study to demonstrate that COX189 (400mg od) reduces the risk to develop complicated ulcers as compared to NSAIDs (naproxen 500 mg bid and ibuprofen 800 mg tid), in osteoarthritis patients.

2001-2002

ZIMMER Ltd

A Clinical Outcome Study:
Hip Arthroplasty Using Trabecular Metal Technology Acetabular Cup.

2002

BOEHRINGER INGELHEIM

The influence of non-steroidal anti- infammatory drugs on fracture union.

2002

NOVARTIS

Distal Radius fractures and Calcitonin.

2002

Various Sponsors

Research protocol on Hand Fractures.

2002

IMPLEX CORP. – New Jersey, USA

HEDROCEL Trabecular Metal Technology of IMPLEX

Various Sponsors

Maintenance – functional outcome of the Arthroplasty of the Hip and Knee.

Various Sponsors

The relevance of the expansion of the lesion in avascular necrosis of the femoral head with the clinical outcome. Three dimensional analysis and estimation of the volume of the lesion with the ANALYZE system.

2002

ZIMMER Ltd

Porous Tantalum (Trabecular Metal) implants for femoral head osteonecrosis: (a) the Acetabular metal ring, (b) the Intra-lesion implant.

2004

SANOFI SYNTHELABO

EXPERT: C8843
The use of Fondaparinux sodium (Arixtra®) on a daily basis in patients undergoing major Orthopaedic surgery in the lower limb.

2004

SANOFI SYNTHELABO

A prospective, uncontrolled, multi-centre, post-marketing surveillance study to evaluate the long-term performance of summit tapered Hip in Cemented Total Hip Arthroplasty.

2004

NOVARTIS

CZOL446H 2310: A multinational, multicentre, multiple-dose, randomized, double-blind, double dummy, parallel group study with a long term open-label extension phase for the evaluation of the zoledronic acid in the prevention of future osteoporotic hip fractures.

2004-2005

VIANEX

A double-blind, parallel-group, 4-week trial to assess the efficacy and safety of Etoricoxib 60 mg and Diclofenac 150 mg in patients with Chronic Low Back Pain.

2006

Various Sponsors

Use of ultrasound for the enhancement of healing of Cartilage Tissues. 

2006

NOVARTIS AE

The effect of the calcitonin administration on the healing of fracture and osteopenia of the patient, in patients with fractures in the periphery of the fibula.

2006

ROCHE (HELLAS) A.E.

BEATRIS study: A randomized, open, multinational study of the effect of information related to osseous markers (in a two-month period) in the total compliance in the monthly treatment with ibandronate acid in postmenopausal osteoporosis.

2007

SANOFI AVENTIS

Trek – DRI 6243: a multi-centre, randomized, double-blind, double-dummy, parallel group dose-response study of subcutaneous AVE 5026 with an enoxaparin calibrator arm in the prevention of Venous Thromboembolism in patients undergoing Elective Total Knee Replacement Surgery.

2007

NOVARTIS Hellas AEBE

Eu-CORESM: European CUBICIN® Outcomes Registry and Experience for the Treament of Serious Gram-positive Infections.

2007

SANOFI AVENTIS Hellas

ETHOS Clinical Trial:
Evaluation of duration Thromboemblolic prophylaxis after major Orthopaedic Surgery.

2007

SANOFI AVENTIS AEBE

Clinical Trial EFC 10343 – SAVE HIP 2:
A multinational, multi-centre, randomized, double-blind study comparing the efficacy and safety of AVE5026 with enoxaparin for the prevention of Venous Thromboembolism (VTE) in patients undergoing Hip Fracture Surgery.

2007

DEPUY

A prospective, international, multi-centre, uncontrolled, post- marketing surveillance study to monitor the long-time performance of a large Metal-on-Metal (MoM) bearing comprising a DePuy ASRTM cup in conjunction with either a DePuy ASRTM hip resurfacing femoral component or a DePuy ASR TM XL Head in subjects with indications suitable for either a primary resurfacing arthroplasty or primary Total Hip Arthroplasty.


2008

NYCOMED Danmark, Aps

PAREXEL Number: 90383
A 24-week, international, multi-centre, randomized, double-blind, double-dummy, parallel group, phase IV clinical trial investigating changes in postmenopausal women with an osteoporosis-related vertebral fracture(s) treated with either 100 μg PTH (1-84) daily or 70 mg alendronate weekly.

2008

PHARMASERVE- LILLY

B3D-EW-GHDK (EudraCT: 2008-002693-35) A comparison of the effect of Teriparatide with that of Risedronate in the bone density of the lumbar spine in men and postmenopausal women with low bone mass and a recent intertrochanteric fracture.

 
 

 2017 Department of Orthopaedic Surgery & Musculoskeletal Trauma, University of Thessalia

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